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...... | Introducing.............
Strontium - The First Bone-Building Supplement!
Bone loss accelerates suddenly in menopausal women because the drop in
estrogen levels causes an increase in the resorption (teardown) of
existing
bone. But resorption is only half of the story. Age-related bone loss
is
also caused by a decrease in the formation of new bone
tissue.
Existing
drugs for treating osteoporosis, as well as calcium and vitamin D
supplements,
work by reducing bone resorption. But they do not support the formation
of new bone. These drugs and nutrients increase the mineralization of
bone,
but they do not help the body to build new bone tissue. And
in
fact,
within weeks of starting use of antiresorptive drugs like
Fosamax®,
the body’s formation of new bone actually
decreases.
The resulting bone is less prone to fracture, but is not the same as
youthful,
healthy bone. If you would like to read more about antiresorptive drugs and the latest information on their effectiveness, please click here to go an article by Byron Richards, clinical nutritionist, author, and leading natural health expert. If you are considering starting on Boniva® you will also want to read |
Strontium is a mineral found
along
with
calcium in most foods. Research has long suggested that it may be an
essential
nutrient required for the normal development, structure, function, and
health of the skeletal system. Clinical trials going back
into
the
1940s have supported this conclusion, but recent studies have provided
evidence that it can offer unique nutritional support against loss of
bone
structure and function. Animal studies have shown that Strontium
supplements
both decrease bone resorption, and increase the formation of new bone
tissue.
•In animal models, Strontium (in various forms, such as
chloride,
carbonate,
gluconate, and lactate) causes “baby”
osteoblasts
(bone-building
cells) to multiply more quickly.
•Bone tissue cultures which are exposed to Strontium
synthesize
more bone
matrix and new bone collagen. The same amount of calcium has no effect
on
these parameters.
•In bone tissue culture, Strontium reduces bone resorption at
concentrations
at which calcium has no effect, prevents the resorption caused by
excessive
parathyroid hormone, and slows the rate at which immature osteoclasts
develop.
•Strontium-supplemented diets boost bone strength in
experimental
animals
without a negative impact on bone quality, even at extremely high doses.
Human
clinical trials also support
Strontium’s
ability to both support new bone formation and prevent excessive
resorption.
•The results of early clinical trials using Strontium
(lactate)
led researchers
to speculate that Strontium increased osteoblast activity.
•Bone biopsies from a small human pilot trial revealed an
astounding 172.4%
increase in new bone formation after six months of Strontium (gluconate)
supplementation.
•The bone-building activity of osteoblasts can be measured
using
bone-specific
alkaline phosphatase, while crosslinked N-telopeptide (NTx)
and
C-telopeptide
(CTx) mark the degradation
of bone collagen by ravaging osteoclasts. Unlike the range of
side-effects
that accompany antiresorptive drugs, no clinical side-effects have ever
been reported that could be clearly attributed to Strontium.
Calcium
and Strontium: the Dynamic Tension
Calcium and Strontium can both play key roles in the health of your
bones
– if you use them properly. On the one hand, animal studies
suggest that
Strontium is not effective, and may even be counterproductive, if your
calcium intake is not adequate. Current “official”
recommendations suggest
an intake of 1000 milligrams of calcium for younger adults, and 1200
milligrams
for people over the age of 50. Some evidence suggests that a still
higher
intake (1300-1600 milligrams) of calcium is more effective
for
lowering
fracture risk in the elderly. But remember that these numbers are your
total calcium need. The more calcium you get in your diet, the less you
need from supplements.
At the same time,
however,
it’s important not
to take your Strontium supplement at
the same
time as your calcium
supplements. This is because calcium and
Strontium
use the same pathways for absorption in the intestinal tract, so that
swallowing
a calcium supplement along with your Strontium can dramatically reduce
absorption. So obviously, putting Strontium and calcium in
the
same
pill is a recipe for bone health disaster, in which you don’t
get
the benefits
of either nutrient!
The
best protocol – and
the one used in the most recent clinical
trials
– is to take your Strontium either three hours after your
last
meal of
the day, or one hour before breakfast in the morning, or both. Because
studies suggest that one last dose of calcium just before retiring can
help prevent excessive resorption of bone overnight, it
may be best
to take all of your Strontium before breakfast, leaving you free to
take
a calcium supplement just before you go to bed.
Like the
Strontium
carbonate crystals (strontianite) from which it was first
isolated,
Strontium’s role in bone health has long been hidden in
obscurity. But
its strength has allowed it to endure, waiting for the day that it
could
emerge and reveal its power.
References
1 Sips, AJAM et-al. Intestinal absorption of strontium chloride in
healthy volunteers: pharmacokinetics and reproducibility.Br. J Clin
Pharmacol.
1996;41:543-549
2 Sips, AJAM.Absoption kinetics of strontium and calcium in human and
experimental
animal.
Ph.D Thesis. University of Amsterdam. 1994
3 Skoryna, SC. Effects of oral supplementation with stable strontium.
Can
Med J.
1981;125:703-712
4 ATSDR.Toxicological profile for strontium. Atlanta,GA: Agency for
toxic
substances and
disease registry US Dept of Health and Human Services. Public Health
Services.2001
5 Leeuwenkamp,OR et-al. Human pharmacokinetics of orally administered
strontium.
Calcif.
Tissue Int. 1990;47:136-140
6 Marie,PJ et-al. Effect of low doses of stable strontium on bone
metabolism
in rats. Mineral
Electrolyte Metab. 1985;11:5-13
7 Shorr, E and Carter, AC. The value of strontium as an adjuvant to
calcium
in the mineralization
of the skeleton in osteoporosis in man. Conference on Metabolic
Interactions.
Eds. EC
Reifenstein Jr.,NY.NY.Pub J Macy Foundation 1950 pp144-154.
8 McCaslin FE and Janes, HM. The effect of strontium lactate in the
treatment
of osteoporosis.
Proc. Mayo Clinic. 1959;34:329-334
9 Skoryna,SC and Fuskova, M. In: Skoryna, SC ed. Handbook of stable
strontium.NY;Plenum:1985.p593-617
10 Comar,CL , Wasserman, RH and Nold, NM. Strontium-Calcium
discrimination
factors in the
rat. Proc. Sco. Exp. Biol. Med.1950;92:859-863
11 Della Rossa et-al. Absorption and retention of ingested strontium
and
calcium in beagles as a
function of age. Nature.1965;205:197-198
12 Skoryna, SC.Metabolic aspects of the pharmacologic uses of trace
elements
in human
subjects with specific references to stable strontium. Trace Subst.
Enviorn
Health.1984;18:3-23
13 Dahl, SG et-al. Incorporation and distribution of strontium in bone.
Bone.2001;28:446-453
14 Storey,E. Strontium “rickets” bone calcium and
strontium
changes. Austral.Ann.
Med.
1961;10:213-222
15 Matsumoto, A. Effect of strontium chloride on bone resorption
induced
by prostaglandin E2 in
cultured bone. Arch. Toxicol. 1988;62:240-241
16 Marie,PJ et-al. Mechanisms of action and therapeutic potential of
strontium
in bone. Calcif.
Tissue Int.2001;69:121-129.
The information and product descriptions appearing on this website are
for information purposes
only, and are not intended to provide medical advice to individuals.
Consult
with your physician if
you have any health concerns, and before initiating any new diet,
exercise,
supplement, or other
lifestyle changes.
To order call 888-660-8831 or order online at www.naturallybetter.net
Strontium
Support Supplement Fact
Osteoporosis Prevention
Testimonials
of those who are using Strontium
Link
to Dr Jonathan Wright's Newsletter on Osteoporosis
(This newsletter is a "must read" if you are using or considering
prescription
meds for osteoporosis)
Be sure to click back
here to order the Strontium Dr.
Wright recommends from AOR (the
best
strontium available)
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this
page
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